Is Dry Mouth or Cotton Mouth a Cannabis Side-Effect?

Saliva plays a crucial role in the oral cavity. It helps digest food and maintain a healthy balance of bacterial flora in the mouth. The daily production of saliva normally ranges from 0.5 to 1.5 liters in healthy individuals. A lack of this salivary production, known as dry mouth, can lead to significant discomfort.

woman hold her mouth


What is cotton mouth?

Cotton mouth is a term that describes symptoms of dry mouth or xerostomia. Many people suffer from dry mouth and it appears to be a common condition. 1 in 4 people are affected by xerostomia due to medication side-effect or underlying diseases, annually.

Common side effects of cotton mouth


There are several side-effects caused by cotton mouth:


  • Frequent thirst
  • Cracked lips 
  • Open sores in the mouth 
  • Dry/ red tongue
  • Difficulty chewing, swallowing or speaking
  • Poor dental hygiene
  • Increased plaque
  • Tooth decay
  • Gum Disease and more
side effects of cotton mouth
Describes the common causes of dry mouth

Common causes of dry mouth or cotton mouth


Dry Mouth or cotton mouth can be caused by the following medical and non-medical conditions:

  • Frequent Cannabis use
  • Dehydration
  • Medication side-effects
  • Age
  • Pregnancy & hormonal changes
  • Tobacco and alcohol use
  • Increased Caffeine intake
  • And more

Can Cannabis cause cotton mouth?

Cotton mouth is a common a side-effect of Cannabis use!

Even though more research is currently on-going on the effects of Cannabis use, we know that dry mouth is a side effect of both CBD (cannabidiol) and THC (tetrahydrocannabinol) – the primary active compounds or cannabinoids, found in Cannabis plants. Cannabis studies show that cannabidiol (CBD) – the non-psychoactive, therapeutic active ingredient in marijuana, – binds to cannabinoid receptors in the salivary glands, causing them to be hypoactive. When this occurs, signaling from the brain that normally tell the submandibular glands reduce the production of saliva resulting in dry mouth or cotton mouth.


Our body has an endocannabinoid system (ECS), consisting of naturally occurring cannabinoids and cannabinoid receptors, and has many functions in the body. Cannabinoid receptors are found on the submandibular glands, a pair of glands located beneath the floor of the mouth that are responsible for producing about 70% of our saliva. Hence when Cannabis is ingested or inhaled, the cannabinoids in the Cannabis bind to the cannabinoid receptors on the salivary glands, blocking it from sending messages to the parasympathetic nervous system. In other words, your nervous system fails to receive a message to maintain adequate salivary flow, leading to dry mouth.

As you can see, cotton mouth is, in fact, a common side-effect of Cannabis.

Dry mouth (xerostomia) is dose-dependent, meaning it becomes stronger with heavier Cannabis use. People commonly experience cotton mouth with ingestion and vaporization of Cannabis, without inhalation of smoke, because CBD directly affects the salivary glands.

What can you do to treat cotton mouth?

Cannabis-associated cotton mouth, can be quite uncomfortable. There are several home remedies that you can try to ease your symptoms, namely:

  • Drink more water
  • Xylitol gum
  • Reduce the use of Cannabis (as Cotton mouth is dose-dependent)
  • Avoid alcohol (including in mouthwash)
  • Reduce caffeine intake
  • Reduce tobacco use
  • Try Natural Dry Mouth Spray, Lubricity!

What is Lubricity?

Lubricity is a Natural Dry Mouth Spray that works! Our simple and effective formulation is a breakthrough in the treatment of xerostomia.  Lubricity’s formula includes hyaluronic acid, an ingredient that helps seal in the mouth’s natural moisture creating a soothing and hydrated feeling.

Lubricity Dry Mouth Spray has 5 simple, natural ingredients: Hyaluronic Acid, Xylitol, Sodium Benzoate, Potassium Sorbate and Purified Water. This simple formula is clinically proven to alleviate your dry mouth symptoms for up to 4 hours.

Lubricity is an odorless, flavorless, and colorless spray that is perfect for people who are very sensitive to taste. Our Dry Mouth Spray also has Zero Calories, NO Gluten, NO Alcohol, NO Sugar, and is Vegan-Friendly!!

How to use Lubricity?

Lubricity Dry Mouth Spray comes in a convenient 0.5 oz and 2oz spray bottle. Simply point and spray 3-5 times per use. When used as directed, Lubricity provides up to 4 hours of relief from cotton mouth symptoms experienced with Cannabis use. *Some may need 3-5 pumps per use, as the bottle needs to be primed upon opening.

For best results, we recommend using Lubricity Dry Mouth Spray as follows: 
4 times Per day
4 Pumps per use
4 Hours of relief

Important: If you are pregnant or breastfeeding, please consult your physician before using Lubricity. DO not use Lubricity if you are taking any medications that are contraindicated with the product. Please consult with your physician if you have any concerns regarding the use of this product. Keep out of reach of children.

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